Synthesis of 6-(2-Amino-2-deoxy-β-D-glucopyranosylamino)- and 6-(β-D-Glucopyranosylamino)purine
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چکیده
منابع مشابه
N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity
Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside is a synthetic saponin exhibiting attractive pharmacological properties. Different pathways tested by us to obtain this glycoside are summarized here. Moreover, the synthesis of N-alkyl and N,N-dialkyl derivatives of the glucopyranoside is presented. Evaluation of antibacterial and antifungal activities of these derivatives indicates that they have ...
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Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside (β-GlcNAcOCH(3)), (I), crystallizes from water as a dihydrate, C(9)H(17)NO(6)·H(2)O, containing two independent molecules [denoted (IA) and (IB)] in the asymmetric unit, whereas the crystal structure of methyl 2-formamido-2-deoxy-β-D-glucopyranoside (β-GlcNFmOCH(3)), (II), C(8)H(15)NO(6), also obtained from water, is devoid of solvent water molecul...
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The synthesis of diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside is presented for the first time. This synthetic saponin was transformed into its hydrochloride as well as N-acyl, 2-ureido, N-alkyl, and N,N-dialkyl derivatives. Antifungal and antibacterial studies show that some of the obtained compounds are active against Gram-positive bacteria and Candida type fungi.
متن کاملSynthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives
Heterocyclic systems are one of the most important classes of organic compounds present in nature or synthesized in laboratory. These compounds posses an array of biological activities and are employed in the treatment of commonly occurring diseases. Keeping this in view, some new 2-amino-4,6-diarylpyrimidine from chalcones were synthesized. Eight novel 2-amino-4,6-diarylpyrimidine derivatives ...
متن کاملsynthesis and in vitro antibacterial activity of some novel 2-amino-4, 6-d derivatives
heterocyclic systems are one of the most important classes of organic compounds present in nature or synthesized in laboratory. these compounds posses an array of biological activities and are employed in the treatment of commonly occurring diseases. keeping this in view, some new 2-amino-4,6-diarylpyrimidine from chalcones were synthesized. eight novel 2-amino-4,6-diarylpyrimidine derivatives ...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1974
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.47.917